Hand sanitizer effective against COVID-19 is available to all guest at our front entrance.Many condiments will be available in single-use packets. Condiments will be brought to the table on request and multi-use bottles/dispensers will be disinfected between guests.Single-use place mat menus, paper bag sleeves with silverware, and napkins are provided after the guest is seated.Employees will thoroughly clean and disinfect tables and chairs between guests with approved EPA List N disinfectant.All employees will have COVID Serv Safe training and a current food handler’s card.Outdoors: customers from up to eight (8) households may be seated together as a party of eight if they are fully vaccinated. Indoors: customers from up to six (6) households may be seated together as a party of six if they are all fully vaccinated.Sneeze and cough into a cloth or tissue or, if not available, into one's elbow.Do no shake hands or engage in any unnecessary physical contact.Please maintain six-foot minimum social distancing.Guests may be asked to supply contact information before entering the facility to allow for contact tracing should this be required.Guests are required to wear face coverings until they are seated at their table.All employees and customers are prohibited from entering the facility if they have a cough, fever, shortness of breath or difficulty breathing, chills, muscle pain, sore throat, or new loss of taste or smell.We are excited to serve you! Thank you again for your patience and cooperation as we all adjust to these necessary protocols. We will also be strictly following the county’s guidance for dine-in restaurants by limiting seating, requesting all our guests to join our wait list through Yelp and provide your parties contact information, requiring our staff to use masks, face shields, and gloves, constant cleaning and sanitation, and many other precautionary measures to protect the health of our guests and employees. Please wear a face covering until you are seated and your food is served to help us comply with this order. Further evaluation of nano-OPH as a catalytic bioscavenger countermeasure against organophosphorus chemical warfare agents and pesticides is warranted.Thank you to our community for your continued support, and thank you in advance for your patience and cooperation as we work to safely reopen our doors.Īs part of our reopening certification agreement with the State and county, LA county requires that face coverings to be worn in public places. In particular, a complete protection against the lethal doses of paraoxon was observed with nano-OPH administered iv and ip as much as 17 h, im 5.5 h and tb 2 h before the intoxication. Moreover, nano-OPH is bioavailable after intramuscular ( im), intraperitoneal ( ip) and even transbuccal ( tb) administration, and has shown ability to protect animals from exposure to a pesticide, paraoxon and a warfare agent, VX. The nano-OPH pharmacokinetic parameters are improved compared to the naked enzyme suggesting longer blood circulation after intravenous ( iv) administrations in rats. It also decreases the immune and inflammatory responses to His 6-OPH in vivo as determined by anti-OPH IgG and cytokines formation in Sprague Dawley rats and Balb/c mice, respectively.
Incorporation of His 6-OPH in nano-OPH preserves catalytic activity and increases stability of the enzyme allowing its storage in aqueous solution for over a year. The resulting polyion complex, termed nano-OPH, has a spherical morphology and a diameter from 25 nm to 100 nm. A simple and highly efficient catalytic scavenger of poisonous organophosphorus compounds, based on organophosphorus hydrolase (OPH, EC 3.1.8.1), is produced in aqueous solution by electrostatic coupling of the hexahistidine tagged OPH (His 6-OPH) and poly(ethylene glycol)- b-poly( l-glutamic acid) diblock copolymer.